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Dose and Schedule Selection of the Oral Proteasome Inhibitor Ixazomib in Relapsed/Refractory Multiple Myeloma: Clinical and Model-Based Analyses
BACKGROUND: The oral proteasome inhibitor ixazomib has been approved by regulatory authorities around the world, including in the United States and the European Union, for the treatment of patients with multiple myeloma (MM) who have received at least one prior therapy, based on the pivotal phase II...
Autores principales: | Gupta, Neeraj, Yang, Huyuan, Hanley, Michael J., Zhang, Steven, Liu, Rachael, Kumar, Shaji, Richardson, Paul G., Skacel, Tomas, Venkatakrishnan, Karthik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610674/ https://www.ncbi.nlm.nih.gov/pubmed/28803351 http://dx.doi.org/10.1007/s11523-017-0524-3 |
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