QSAR Study of 17β-HSD3 Inhibitors by Genetic Algorithm-Support Vector Machine as a Target Receptor for the Treatment of Prostate Cancer

The 17β-HSD3 enzyme plays a key role in treatment of prostate cancer and small inhibitors can be used to efficiently target it. In the present study, the multiple linear regression (MLR), and support vector machine (SVM) methods were used to interpret the chemical structural functionality against th...

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Detalles Bibliográficos
Autores principales: Pourbasheer, Eslam, Vahdani, Saadat, Malekzadeh, Davood, Aalizadeh, Reza, Ebadi, Amin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610752/
https://www.ncbi.nlm.nih.gov/pubmed/29201087

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