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Evaluation of a (99m)Tc-tricine Vascular Disrupting Agent as an In-vivo Imaging in 4T1 Mouse Breast Tumor Model

Colchicine as a vascular disrupting agent creates microtubule destabilization which induces vessel blockage and consequently cell death. Accordingly, colchicines and its analogues radiolabeled with (99m)Tc may have potential for visualization of tumor. In this work, deacetylcolchicine a colchicine a...

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Detalles Bibliográficos
Autores principales: Erfani, Mostafa, Shirmardi, Seyed Pezhman, Shafiei, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610754/
https://www.ncbi.nlm.nih.gov/pubmed/29201088