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The relationship between self-reported borderline personality features and prospective illness course in bipolar disorder

BACKGROUND: Although bipolar disorder (BD) and borderline personality disorder (BPD) share clinical characteristics and frequently co-occur, their interrelationship is controversial. Especially, the differentiation of rapid cycling BD and BPD can be troublesome. This study investigates the relations...

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Autores principales: Riemann, Georg, Weisscher, Nadine, Post, Robert M., Altshuler, Lori, McElroy, Susan, Frye, Marc A., Keck, Paul E., Leverich, Gabriele S., Suppes, Trisha, Grunze, Heinz, Nolen, Willem A., Kupka, Ralph W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610955/
https://www.ncbi.nlm.nih.gov/pubmed/28944443
http://dx.doi.org/10.1186/s40345-017-0100-x
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author Riemann, Georg
Weisscher, Nadine
Post, Robert M.
Altshuler, Lori
McElroy, Susan
Frye, Marc A.
Keck, Paul E.
Leverich, Gabriele S.
Suppes, Trisha
Grunze, Heinz
Nolen, Willem A.
Kupka, Ralph W.
author_facet Riemann, Georg
Weisscher, Nadine
Post, Robert M.
Altshuler, Lori
McElroy, Susan
Frye, Marc A.
Keck, Paul E.
Leverich, Gabriele S.
Suppes, Trisha
Grunze, Heinz
Nolen, Willem A.
Kupka, Ralph W.
author_sort Riemann, Georg
collection PubMed
description BACKGROUND: Although bipolar disorder (BD) and borderline personality disorder (BPD) share clinical characteristics and frequently co-occur, their interrelationship is controversial. Especially, the differentiation of rapid cycling BD and BPD can be troublesome. This study investigates the relationship between borderline personality features (BPF) and prospective illness course in patients with BD, and explores the effects of current mood state on self-reported BPF profiles. METHODS: The study included 375 patients who participated in the former Stanley Foundation Bipolar Network. All patients met DSM-IV criteria for bipolar-I disorder (n = 294), bipolar-II disorder (n = 72) or bipolar disorder NOS (n = 9). BPF were assessed with the self-rated Personality Diagnostic Questionnaire. Illness course was based on 1-year clinician rated prospective daily mood ratings with the life chart methodology. Regression analyses were used to estimate the relationships among these variables. RESULTS: Although correlations were weak, results showed that having more BPF at baseline is associated with a higher episode frequency during subsequent 1-year follow-up. Of the nine BPF, affective instability, impulsivity, and self-mutilation/suicidality showed a relationship to full-duration as well as brief episode frequency. In contrast all other BPF were not related to episode frequency. CONCLUSIONS: Having more BPF was associated with an unfavorable illness course of BD. Affective instability, impulsivity, and self-mutilation/suicidality are associated with both rapid cycling BD and BPD. Still, many core features of BPD show no relationship to rapid cycling BD and can help in the differential diagnosis.
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spelling pubmed-56109552017-10-10 The relationship between self-reported borderline personality features and prospective illness course in bipolar disorder Riemann, Georg Weisscher, Nadine Post, Robert M. Altshuler, Lori McElroy, Susan Frye, Marc A. Keck, Paul E. Leverich, Gabriele S. Suppes, Trisha Grunze, Heinz Nolen, Willem A. Kupka, Ralph W. Int J Bipolar Disord Research BACKGROUND: Although bipolar disorder (BD) and borderline personality disorder (BPD) share clinical characteristics and frequently co-occur, their interrelationship is controversial. Especially, the differentiation of rapid cycling BD and BPD can be troublesome. This study investigates the relationship between borderline personality features (BPF) and prospective illness course in patients with BD, and explores the effects of current mood state on self-reported BPF profiles. METHODS: The study included 375 patients who participated in the former Stanley Foundation Bipolar Network. All patients met DSM-IV criteria for bipolar-I disorder (n = 294), bipolar-II disorder (n = 72) or bipolar disorder NOS (n = 9). BPF were assessed with the self-rated Personality Diagnostic Questionnaire. Illness course was based on 1-year clinician rated prospective daily mood ratings with the life chart methodology. Regression analyses were used to estimate the relationships among these variables. RESULTS: Although correlations were weak, results showed that having more BPF at baseline is associated with a higher episode frequency during subsequent 1-year follow-up. Of the nine BPF, affective instability, impulsivity, and self-mutilation/suicidality showed a relationship to full-duration as well as brief episode frequency. In contrast all other BPF were not related to episode frequency. CONCLUSIONS: Having more BPF was associated with an unfavorable illness course of BD. Affective instability, impulsivity, and self-mutilation/suicidality are associated with both rapid cycling BD and BPD. Still, many core features of BPD show no relationship to rapid cycling BD and can help in the differential diagnosis. Springer Berlin Heidelberg 2017-09-25 /pmc/articles/PMC5610955/ /pubmed/28944443 http://dx.doi.org/10.1186/s40345-017-0100-x Text en © The Author(s) 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Research
Riemann, Georg
Weisscher, Nadine
Post, Robert M.
Altshuler, Lori
McElroy, Susan
Frye, Marc A.
Keck, Paul E.
Leverich, Gabriele S.
Suppes, Trisha
Grunze, Heinz
Nolen, Willem A.
Kupka, Ralph W.
The relationship between self-reported borderline personality features and prospective illness course in bipolar disorder
title The relationship between self-reported borderline personality features and prospective illness course in bipolar disorder
title_full The relationship between self-reported borderline personality features and prospective illness course in bipolar disorder
title_fullStr The relationship between self-reported borderline personality features and prospective illness course in bipolar disorder
title_full_unstemmed The relationship between self-reported borderline personality features and prospective illness course in bipolar disorder
title_short The relationship between self-reported borderline personality features and prospective illness course in bipolar disorder
title_sort relationship between self-reported borderline personality features and prospective illness course in bipolar disorder
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610955/
https://www.ncbi.nlm.nih.gov/pubmed/28944443
http://dx.doi.org/10.1186/s40345-017-0100-x
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