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CD28 Blockade Ex Vivo Induces Alloantigen-Specific Immune Tolerance but Preserves T-Cell Pathogen Reactivity

Donor T-cells contribute to reconstitution of protective immunity after allogeneic hematopoietic stem cell transplantation (HSCT) but must acquire specific tolerance against recipient alloantigens to avoid life-threatening graft-versus-host disease (GvHD). Systemic immunosuppressive drugs may abroga...

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Detalles Bibliográficos
Autores principales:	Dillinger, Barbara, Ahmadi-Erber, Sarah, Soukup, Klara, Halfmann, Angela, Schrom, Silke, Vanhove, Bernard, Steinberger, Peter, Geyeregger, Rene, Ladisch, Stephan, Dohnal, Alexander Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611377/ https://www.ncbi.nlm.nih.gov/pubmed/28979262 http://dx.doi.org/10.3389/fimmu.2017.01152

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