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A Rare Case of Aggressive Melanotic Schwannoma Occurred in Spinal Nerve of a 59-Year-Old Male

Melanotic schwannoma (MS) is a rare variant of nerve sheath neoplasm that shows ultrastructural and immunophenotypical features of Schwann cells but also has cytoplasmic melanosomes and is reactive for melanocytic markers as well. Unlike conventional schwannoma, which is totally benign, MS has an un...

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Autores principales: Choi, Sung-eun, Cha, Yoon Jin, Kim, Jisup, Cha, Hyunseo, Seo, Jayeong, Kuh, Sung-Uk, Kim, Sung-Jun, Kim, Se Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Pathologists and the Korean Society for Cytopathology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611526/
https://www.ncbi.nlm.nih.gov/pubmed/28372342
http://dx.doi.org/10.4132/jptm.2017.01.04
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author Choi, Sung-eun
Cha, Yoon Jin
Kim, Jisup
Cha, Hyunseo
Seo, Jayeong
Kuh, Sung-Uk
Kim, Sung-Jun
Kim, Se Hoon
author_facet Choi, Sung-eun
Cha, Yoon Jin
Kim, Jisup
Cha, Hyunseo
Seo, Jayeong
Kuh, Sung-Uk
Kim, Sung-Jun
Kim, Se Hoon
author_sort Choi, Sung-eun
collection PubMed
description Melanotic schwannoma (MS) is a rare variant of nerve sheath neoplasm that shows ultrastructural and immunophenotypical features of Schwann cells but also has cytoplasmic melanosomes and is reactive for melanocytic markers as well. Unlike conventional schwannoma, which is totally benign, MS has an unpredictable prognosis and is thought to have low-malignant potential. Herein, we present a rare case of recurrent MS in lumbar spine of a 59-year-old male.
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spelling pubmed-56115262017-09-27 A Rare Case of Aggressive Melanotic Schwannoma Occurred in Spinal Nerve of a 59-Year-Old Male Choi, Sung-eun Cha, Yoon Jin Kim, Jisup Cha, Hyunseo Seo, Jayeong Kuh, Sung-Uk Kim, Sung-Jun Kim, Se Hoon J Pathol Transl Med Case Study Melanotic schwannoma (MS) is a rare variant of nerve sheath neoplasm that shows ultrastructural and immunophenotypical features of Schwann cells but also has cytoplasmic melanosomes and is reactive for melanocytic markers as well. Unlike conventional schwannoma, which is totally benign, MS has an unpredictable prognosis and is thought to have low-malignant potential. Herein, we present a rare case of recurrent MS in lumbar spine of a 59-year-old male. The Korean Society of Pathologists and the Korean Society for Cytopathology 2017-09 2017-04-04 /pmc/articles/PMC5611526/ /pubmed/28372342 http://dx.doi.org/10.4132/jptm.2017.01.04 Text en © 2017 The Korean Society of Pathologists/The Korean Society for Cytopathology This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Study
Choi, Sung-eun
Cha, Yoon Jin
Kim, Jisup
Cha, Hyunseo
Seo, Jayeong
Kuh, Sung-Uk
Kim, Sung-Jun
Kim, Se Hoon
A Rare Case of Aggressive Melanotic Schwannoma Occurred in Spinal Nerve of a 59-Year-Old Male
title A Rare Case of Aggressive Melanotic Schwannoma Occurred in Spinal Nerve of a 59-Year-Old Male
title_full A Rare Case of Aggressive Melanotic Schwannoma Occurred in Spinal Nerve of a 59-Year-Old Male
title_fullStr A Rare Case of Aggressive Melanotic Schwannoma Occurred in Spinal Nerve of a 59-Year-Old Male
title_full_unstemmed A Rare Case of Aggressive Melanotic Schwannoma Occurred in Spinal Nerve of a 59-Year-Old Male
title_short A Rare Case of Aggressive Melanotic Schwannoma Occurred in Spinal Nerve of a 59-Year-Old Male
title_sort rare case of aggressive melanotic schwannoma occurred in spinal nerve of a 59-year-old male
topic Case Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611526/
https://www.ncbi.nlm.nih.gov/pubmed/28372342
http://dx.doi.org/10.4132/jptm.2017.01.04
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