Cargando…

Chemical composition and antioxidant potentials of Kigelia pinnata root oil and extracts

The chemical composition of Kigelia pinnata root oil extracted with n-hexane was analyzed by GC/GCMS. The antioxidant potential of the oil was compared to that of ethyl acetate and methanol extracts of the root. UV and IR spectroscopic techniques were used to carry out partial characterization of th...

Descripción completa

Detalles Bibliográficos
Autores principales: Atolani, Olubunmi, Adeyemi, Stephen O., Akpan, Essiet, Adeosun, Charles B., Olatunji, Gabriel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611606/
https://www.ncbi.nlm.nih.gov/pubmed/29033707
_version_ 1783265982323621888
author Atolani, Olubunmi
Adeyemi, Stephen O.
Akpan, Essiet
Adeosun, Charles B.
Olatunji, Gabriel A.
author_facet Atolani, Olubunmi
Adeyemi, Stephen O.
Akpan, Essiet
Adeosun, Charles B.
Olatunji, Gabriel A.
author_sort Atolani, Olubunmi
collection PubMed
description The chemical composition of Kigelia pinnata root oil extracted with n-hexane was analyzed by GC/GCMS. The antioxidant potential of the oil was compared to that of ethyl acetate and methanol extracts of the root. UV and IR spectroscopic techniques were used to carry out partial characterization of the oil and extracts. The free radical scavenging activity by spectrophotometric assay on the reduction of 1,1-diphenyl-2-picrylhydrazyl (DPPH) was examined while the total antioxidant activity (TAA) and relative antioxidant activity (RAA) were compared with standard antioxidant, α-tocopherol. The antioxidant activity (which correlated with the total phenolic content of the extracts) was assumed to be from the total phenolic content of the extracts. TAA was found to be higher in methanol extract (at 0.25 mg/mL). We hereby report for the first time the major component of the oil from the root of Kigelia pinnata to be elaidic acid (56.12 %). It is a reported toxicant which thereby underscores the risk in the use of the plant in traditional therapies.
format Online
Article
Text
id pubmed-5611606
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher Leibniz Research Centre for Working Environment and Human Factors
record_format MEDLINE/PubMed
spelling pubmed-56116062017-10-13 Chemical composition and antioxidant potentials of Kigelia pinnata root oil and extracts Atolani, Olubunmi Adeyemi, Stephen O. Akpan, Essiet Adeosun, Charles B. Olatunji, Gabriel A. EXCLI J Research Article The chemical composition of Kigelia pinnata root oil extracted with n-hexane was analyzed by GC/GCMS. The antioxidant potential of the oil was compared to that of ethyl acetate and methanol extracts of the root. UV and IR spectroscopic techniques were used to carry out partial characterization of the oil and extracts. The free radical scavenging activity by spectrophotometric assay on the reduction of 1,1-diphenyl-2-picrylhydrazyl (DPPH) was examined while the total antioxidant activity (TAA) and relative antioxidant activity (RAA) were compared with standard antioxidant, α-tocopherol. The antioxidant activity (which correlated with the total phenolic content of the extracts) was assumed to be from the total phenolic content of the extracts. TAA was found to be higher in methanol extract (at 0.25 mg/mL). We hereby report for the first time the major component of the oil from the root of Kigelia pinnata to be elaidic acid (56.12 %). It is a reported toxicant which thereby underscores the risk in the use of the plant in traditional therapies. Leibniz Research Centre for Working Environment and Human Factors 2011-11-30 /pmc/articles/PMC5611606/ /pubmed/29033707 Text en Copyright © 2011 Atolani et al. http://www.excli.de/documents/assignment_of_rights.pdf This is an Open Access article distributed under the following Assignment of Rights http://www.excli.de/documents/assignment_of_rights.pdf. You are free to copy, distribute and transmit the work, provided the original author and source are credited.
spellingShingle Research Article
Atolani, Olubunmi
Adeyemi, Stephen O.
Akpan, Essiet
Adeosun, Charles B.
Olatunji, Gabriel A.
Chemical composition and antioxidant potentials of Kigelia pinnata root oil and extracts
title Chemical composition and antioxidant potentials of Kigelia pinnata root oil and extracts
title_full Chemical composition and antioxidant potentials of Kigelia pinnata root oil and extracts
title_fullStr Chemical composition and antioxidant potentials of Kigelia pinnata root oil and extracts
title_full_unstemmed Chemical composition and antioxidant potentials of Kigelia pinnata root oil and extracts
title_short Chemical composition and antioxidant potentials of Kigelia pinnata root oil and extracts
title_sort chemical composition and antioxidant potentials of kigelia pinnata root oil and extracts
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611606/
https://www.ncbi.nlm.nih.gov/pubmed/29033707
work_keys_str_mv AT atolaniolubunmi chemicalcompositionandantioxidantpotentialsofkigeliapinnatarootoilandextracts
AT adeyemistepheno chemicalcompositionandantioxidantpotentialsofkigeliapinnatarootoilandextracts
AT akpanessiet chemicalcompositionandantioxidantpotentialsofkigeliapinnatarootoilandextracts
AT adeosuncharlesb chemicalcompositionandantioxidantpotentialsofkigeliapinnatarootoilandextracts
AT olatunjigabriela chemicalcompositionandantioxidantpotentialsofkigeliapinnatarootoilandextracts