A novel rare variant R292H in RTN4R affects growth cone formation and possibly contributes to schizophrenia susceptibility

Reticulon 4 receptor (RTN4R) plays an essential role in regulating axonal regeneration and plasticity in the central nervous system through the activation of rho kinase, and is located within chromosome 22q11.2, a region that is known to be a hotspot for schizophrenia (SCZ) and autism spectrum disor...

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Detalles Bibliográficos
Autores principales: Kimura, H, Fujita, Y, Kawabata, T, Ishizuka, K, Wang, C, Iwayama, Y, Okahisa, Y, Kushima, I, Morikawa, M, Uno, Y, Okada, T, Ikeda, M, Inada, T, Branko, A, Mori, D, Yoshikawa, T, Iwata, N, Nakamura, H, Yamashita, T, Ozaki, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611737/
https://www.ncbi.nlm.nih.gov/pubmed/28892071
http://dx.doi.org/10.1038/tp.2017.170

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