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Clinicals And Upper Airway Characteristics in Obese Children with Obstructive Sleep Apnea

INTRODUCTION: Obesity is a factor that is strongly related to the occurrence of obstructive sleep apnea (OSA) in adults, although this association remains controversial for children. OBJECTIVE: The aim of this study was to compare the clinical and upper airway charactheristics, obtained by questionn...

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Autores principales: Martinelli, Eli O, Haddad, Fernanda Louise M, Stefanini, Renato, Moreira, Gustavo A, Rapoport, Priscila B, Gregório, Luis Carlos, Tufik, Sérgio, Bittencourt, Lia Rita A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Brazilian Association of Sleep and Latin American Federation of Sleep 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611765/
https://www.ncbi.nlm.nih.gov/pubmed/28966731
http://dx.doi.org/10.5935/1984-0063.20170001
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author Martinelli, Eli O
Haddad, Fernanda Louise M
Stefanini, Renato
Moreira, Gustavo A
Rapoport, Priscila B
Gregório, Luis Carlos
Tufik, Sérgio
Bittencourt, Lia Rita A
author_facet Martinelli, Eli O
Haddad, Fernanda Louise M
Stefanini, Renato
Moreira, Gustavo A
Rapoport, Priscila B
Gregório, Luis Carlos
Tufik, Sérgio
Bittencourt, Lia Rita A
author_sort Martinelli, Eli O
collection PubMed
description INTRODUCTION: Obesity is a factor that is strongly related to the occurrence of obstructive sleep apnea (OSA) in adults, although this association remains controversial for children. OBJECTIVE: The aim of this study was to compare the clinical and upper airway charactheristics, obtained by questionnaires, physical examination and laboratory tests, among obese children with and without OSA. METHOD: This was aprospective cohort study. 44 obese children (body mass index above the 95th percentile) were included in the study. Questionnaires, physical examination of the upper airway, nasofibrolaryngoscopy, polysomnography, and laboratory allergic tests were performed. RESULTS: There were 22 male patients (50%), and the mean age was 7.6±2.5 years. OSA was present in 19 (43%) patients. There were no statistically significant differences between the groups with and without OSA, in relation to clinical or laboratory allergic parameters. For the upper airway assessments, hypertrophy of the pharyngeal (p=0.001) and palatine (p=0.049) tonsils were the only parameters associated with OSA, and a modified Mallampati index of class III/IV also demonstrated a tendency towards being statistically associated with OSA (p=0.081). Moreover, these findings were confirmed to be factors associated with OSA in this group of children according to a logistic regression analysis. CONCLUSIONS: The occurrence rate of OSA in this obese pediatric population was high. Adenotonsillar hypertrophy and a modified Mallampati index of class III/IV were the factors associated with OSA.
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spelling pubmed-56117652017-09-29 Clinicals And Upper Airway Characteristics in Obese Children with Obstructive Sleep Apnea Martinelli, Eli O Haddad, Fernanda Louise M Stefanini, Renato Moreira, Gustavo A Rapoport, Priscila B Gregório, Luis Carlos Tufik, Sérgio Bittencourt, Lia Rita A Sleep Sci Original Article INTRODUCTION: Obesity is a factor that is strongly related to the occurrence of obstructive sleep apnea (OSA) in adults, although this association remains controversial for children. OBJECTIVE: The aim of this study was to compare the clinical and upper airway charactheristics, obtained by questionnaires, physical examination and laboratory tests, among obese children with and without OSA. METHOD: This was aprospective cohort study. 44 obese children (body mass index above the 95th percentile) were included in the study. Questionnaires, physical examination of the upper airway, nasofibrolaryngoscopy, polysomnography, and laboratory allergic tests were performed. RESULTS: There were 22 male patients (50%), and the mean age was 7.6±2.5 years. OSA was present in 19 (43%) patients. There were no statistically significant differences between the groups with and without OSA, in relation to clinical or laboratory allergic parameters. For the upper airway assessments, hypertrophy of the pharyngeal (p=0.001) and palatine (p=0.049) tonsils were the only parameters associated with OSA, and a modified Mallampati index of class III/IV also demonstrated a tendency towards being statistically associated with OSA (p=0.081). Moreover, these findings were confirmed to be factors associated with OSA in this group of children according to a logistic regression analysis. CONCLUSIONS: The occurrence rate of OSA in this obese pediatric population was high. Adenotonsillar hypertrophy and a modified Mallampati index of class III/IV were the factors associated with OSA. Brazilian Association of Sleep and Latin American Federation of Sleep 2017 /pmc/articles/PMC5611765/ /pubmed/28966731 http://dx.doi.org/10.5935/1984-0063.20170001 Text en http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivative License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium provided the original work is properly cited and the work is not changed in any way.
spellingShingle Original Article
Martinelli, Eli O
Haddad, Fernanda Louise M
Stefanini, Renato
Moreira, Gustavo A
Rapoport, Priscila B
Gregório, Luis Carlos
Tufik, Sérgio
Bittencourt, Lia Rita A
Clinicals And Upper Airway Characteristics in Obese Children with Obstructive Sleep Apnea
title Clinicals And Upper Airway Characteristics in Obese Children with Obstructive Sleep Apnea
title_full Clinicals And Upper Airway Characteristics in Obese Children with Obstructive Sleep Apnea
title_fullStr Clinicals And Upper Airway Characteristics in Obese Children with Obstructive Sleep Apnea
title_full_unstemmed Clinicals And Upper Airway Characteristics in Obese Children with Obstructive Sleep Apnea
title_short Clinicals And Upper Airway Characteristics in Obese Children with Obstructive Sleep Apnea
title_sort clinicals and upper airway characteristics in obese children with obstructive sleep apnea
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611765/
https://www.ncbi.nlm.nih.gov/pubmed/28966731
http://dx.doi.org/10.5935/1984-0063.20170001
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