Cargando…

Baseline Telomere Length and Effects of a Multidomain Lifestyle Intervention on Cognition: The FINGER Randomized Controlled Trial

Leukocyte telomere length (LTL) is a biomarker of aging, and it is associated with lifestyle. It is currently unknown whether LTL is associated with the response to lifestyle interventions. The goal is to assess whether baseline LTL modified the cognitive benefits of a 2-year multidomain lifestyle i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sindi, Shireen, Ngandu, Tiia, Hovatta, Iiris, Kåreholt, Ingemar, Antikainen, Riitta, Hänninen, Tuomo, Levälahti, Esko, Laatikainen, Tiina, Lindström, Jaana, Paajanen, Teemu, Peltonen, Markku, Khalsa, Dharma Singh, Wolozin, Benjamin, Strandberg, Timo, Tuomilehto, Jaakko, Soininen, Hilkka, Kivipelto, Miia, Solomon, Alina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611796/ https://www.ncbi.nlm.nih.gov/pubmed/28777749 http://dx.doi.org/10.3233/JAD-170123

Ejemplares similares

Telomere Length Change in a Multidomain Lifestyle Intervention to Prevent Cognitive Decline: A Randomized Clinical Trial
por: Sindi, Shireen, et al.
Publicado: (2020)

Effect of a Multidomain Lifestyle Intervention on Estimated Dementia Risk
por: Solomon, Alina, et al.
Publicado: (2021)

Associations of Depressive Symptoms and Cognition in the FINGER Trial: A Secondary Analysis of a Randomised Clinical Trial
por: Neuvonen, Elisa, et al.
Publicado: (2022)

Recruitment and Baseline Characteristics of Participants in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)—A Randomized Controlled Lifestyle Trial †
por: Ngandu, Tiia, et al.
Publicado: (2014)

Associations of CAIDE Dementia Risk Score with MRI, PIB-PET measures, and cognition
por: Stephen, Ruth, et al.
Publicado: (2017)

Change in CAIDE Dementia Risk Score and Neuroimaging Biomarkers During a 2-Year Multidomain Lifestyle Randomized Controlled Trial: Results of a Post-Hoc Subgroup Analysis
por: Stephen, Ruth, et al.
Publicado: (2021)

The CAIDE Dementia Risk Score App: The development of an evidence-based mobile application to predict the risk of dementia
por: Sindi, Shireen, et al.
Publicado: (2015)

Healthy Dietary Changes in Midlife Are Associated with Reduced Dementia Risk Later in Life
por: Sindi, Shireen, et al.
Publicado: (2018)

Effect of a multi-domain lifestyle intervention on cardiovascular risk in older people: the FINGER trial
por: Lehtisalo, Jenni, et al.
Publicado: (2022)

Psychosocial determinants for adherence to a healthy lifestyle and intervention participation in the FINGER trial: an exploratory analysis of a randomised clinical trial
por: Neuvonen, Elisa, et al.
Publicado: (2022)

Computer-based cognitive training for older adults: Determinants of adherence
por: Turunen, Merita, et al.
Publicado: (2019)

Cardiovascular health metrics from mid- to late-life and risk of dementia: A population-based cohort study in Finland
por: Liang, Yajun, et al.
Publicado: (2020)

White Matter Changes on Diffusion Tensor Imaging in the FINGER Randomized Controlled Trial
por: Stephen, Ruth, et al.
Publicado: (2020)

Midlife Healthy-Diet Index and Late-Life Dementia and Alzheimer's Disease
por: Eskelinen, Marjo H., et al.
Publicado: (2011)

The Dietary Carbohydrate/Fat-Ratio and Cognitive Performance: Panel Analyses in Older Adults at Risk for Dementia
por: Norgren, Jakob, et al.
Publicado: (2023)

Midlife Work-Related Stress is Associated with Late-Life Gray Matter Volume Atrophy
por: Sindi, Shireen, et al.
Publicado: (2017)

Midlife work-related stress is associated with late-life cognition
por: Sindi, Shireen, et al.
Publicado: (2017)

World-Wide FINGERS: An International Network of Linked Multidomain Trials
por: Mangialasche, Francesca, et al.
Publicado: (2021)

Quantifying dementia prevention potential in the FINGER randomized controlled trial using the LIBRA prevention index
por: Deckers, Kay, et al.
Publicado: (2021)

Brain volumes and cortical thickness on MRI in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)
por: Stephen, Ruth, et al.
Publicado: (2019)

Apolipoprotein E ε4 magnifies lifestyle risks for dementia: a population-based study
por: Kivipelto, Miia, et al.
Publicado: (2008)

Association Between Cognition, Health Related Quality of Life, and Costs in a Population at Risk for Cognitive Decline
por: Janssen, Niels, et al.
Publicado: (2022)

Detecting Amyloid Positivity in Elderly With Increased Risk of Cognitive Decline
por: Pekkala, Timo, et al.
Publicado: (2020)

Development of a Late-Life Dementia Prediction Index with Supervised Machine Learning in the Population-Based CAIDE Study
por: Pekkala, Timo, et al.
Publicado: (2016)

Ketosis After Intake of Coconut Oil and Caprylic Acid—With and Without Glucose: A Cross-Over Study in Healthy Older Adults
por: Norgren, Jakob, et al.
Publicado: (2020)

Serum proBDNF Is Associated With Changes in the Ketone Body β-Hydroxybutyrate and Shows Superior Repeatability Over Mature BDNF: Secondary Outcomes From a Cross-Over Trial in Healthy Older Adults
por: Norgren, Jakob, et al.
Publicado: (2021)

Long‐term dementia risk prediction by the LIBRA score: A 30‐year follow‐up of the CAIDE study
por: Deckers, Kay, et al.
Publicado: (2019)

Association of Peripheral Insulin Resistance and Other Markers of Type 2 Diabetes Mellitus with Brain Amyloid Deposition in Healthy Individuals at Risk of Dementia
por: Pekkala, Timo, et al.
Publicado: (2020)

Multidomain Interventions to Prevent Cognitive Impairment, Alzheimer’s Disease, and Dementia: From FINGER to World-Wide FINGERS
por: Rosenberg, A., et al.
Publicado: (2019)

Third follow-up of the Cardiovascular Risk Factors, Aging and Dementia (CAIDE) cohort investigating determinants of cognitive, physical, and psychosocial wellbeing among the oldest old: the CAIDE85+ study protocol
por: Barbera, Mariagnese, et al.
Publicado: (2020)

27-Hydroxycholesterol, cognition, and brain imaging markers in the FINGER randomized controlled trial
por: Sandebring-Matton, Anna, et al.
Publicado: (2021)

Sex differences in dementia and response to a lifestyle intervention: Evidence from Nordic population‐based studies and a prevention trial
por: Sindi, Shireen, et al.
Publicado: (2021)

Advances in the prevention of Alzheimer's Disease
por: Sindi, Shireen, et al.
Publicado: (2015)

Multidomain interventions: state-of-the-art and future directions for protocols to implement precision dementia risk reduction. A user manual for Brain Health Services—part 4 of 6
por: Solomon, Alina, et al.
Publicado: (2021)

cCOG: A web‐based cognitive test tool for detecting neurodegenerative disorders
por: Rhodius‐Meester, Hanneke F.M., et al.
Publicado: (2020)

Feelings of Hopelessness in Midlife and Cognitive Health in Later Life: A Prospective Population-Based Cohort Study
por: Håkansson, Krister, et al.
Publicado: (2015)

Correction: Feelings of Hopelessness in Midlife and Cognitive Health in Later Life: A Prospective Population-Based Cohort Study
por: Håkansson, Krister, et al.
Publicado: (2015)

Cortisol, cognition and Alzheimer’s disease biomarkers among memory clinic patients
por: Holleman, Jasper, et al.
Publicado: (2022)

Cognitive Performance at Time of AD Diagnosis: A Clinically Augmented Register-Based Study
por: Alenius, Minna, et al.
Publicado: (2022)

Changes in Lifestyle, Behaviors, and Risk Factors for Cognitive Impairment in Older Persons During the First Wave of the Coronavirus Disease 2019 Pandemic in Finland: Results From the FINGER Study
por: Lehtisalo, Jenni, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_v7j3bbk41ll6ag52icvevfcpeo