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Heterogeneous Association of Alzheimer’s Disease-Linked Amyloid-β and Amyloid-β Protein Precursor with Synapses

Alzheimer’s disease (AD) is increasingly viewed as a disease of synapses. Loss of synapses correlates better with cognitive decline than amyloid plaques and neurofibrillary tangles, the hallmark neuropathological lesions of AD. Soluble forms of amyloid-β (Aβ) have emerged as mediators of synapse dys...

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Detalles Bibliográficos
Autores principales:	Willén, Katarina, Sroka, Agnieszka, Takahashi, Reisuke H., Gouras, Gunnar K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611798/ https://www.ncbi.nlm.nih.gov/pubmed/28869466 http://dx.doi.org/10.3233/JAD-170262

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