The Cerebrospinal Fluid Aβ(1–42)/Aβ(1–40) Ratio Improves Concordance with Amyloid-PET for Diagnosing Alzheimer’s Disease in a Clinical Setting

BACKGROUND: Evidence suggests that the concordance between amyloid-PET and cerebrospinal fluid (CSF) amyloid-β (Aβ) increases when the CSF Aβ(1–42)/Aβ(1–40) ratio is used as compared to CSF Aβ(1–42) levels alone. OBJECTIVE: In order to test this hypothesis, we set up a prospective longitudinal study...

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Detalles Bibliográficos
Autores principales: Niemantsverdriet, Ellis, Ottoy, Julie, Somers, Charisse, De Roeck, Ellen, Struyfs, Hanne, Soetewey, Femke, Verhaeghe, Jeroen, Van den Bossche, Tobi, Van Mossevelde, Sara, Goeman, Johan, De Deyn, Peter Paul, Mariën, Peter, Versijpt, Jan, Sleegers, Kristel, Van Broeckhoven, Christine, Wyffels, Leonie, Albert, Adrien, Ceyssens, Sarah, Stroobants, Sigrid, Staelens, Steven, Bjerke, Maria, Engelborghs, Sebastiaan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611891/
https://www.ncbi.nlm.nih.gov/pubmed/28869470
http://dx.doi.org/10.3233/JAD-170327

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