Cargando…

Trimebutine, a small molecule mimetic agonist of adhesion molecule L1, contributes to functional recovery after spinal cord injury in mice

Curing spinal cord injury (SCI) in mammals is a daunting task because of the lack of permissive mechanisms and strong inhibitory responses at and around the lesion. The neural cell adhesion molecule L1CAM (L1) has been shown to favor axonal regrowth and enhance neuronal survival and synaptic plastic...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Junping, Hu, Chengliang, Jiang, Qiong, Pan, Hongchao, Shen, Huifan, Schachner, Melitta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611966/
https://www.ncbi.nlm.nih.gov/pubmed/28714852
http://dx.doi.org/10.1242/dmm.029801

Ejemplares similares