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Discovery of a microbial transglutaminase enabling highly site-specific labeling of proteins
Microbial transglutaminases (MTGs) catalyze the formation of Gln–Lys isopeptide bonds and are widely used for the cross-linking of proteins and peptides in food and biotechnological applications (e.g. to improve the texture of protein-rich foods or in generating antibody-drug conjugates). Currently...
Autores principales: | Steffen, Wojtek, Ko, Fu Chong, Patel, Jigar, Lyamichev, Victor, Albert, Thomas J., Benz, Jörg, Rudolph, Markus G., Bergmann, Frank, Streidl, Thomas, Kratzsch, Peter, Boenitz-Dulat, Mara, Oelschlaegel, Tobias, Schraeml, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612097/ https://www.ncbi.nlm.nih.gov/pubmed/28751378 http://dx.doi.org/10.1074/jbc.M117.797811 |
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