Discovery of pan autophagy inhibitors through a high-throughput screen highlights macroautophagy as an evolutionarily conserved process across 3 eukaryotic kingdoms

Due to the involvement of macroautophagy/autophagy in different pathophysiological conditions such as infections, neurodegeneration and cancer, identification of novel small molecules that modulate the process is of current research and clinical interest. In this work, we developed a luciferase-base...

Descripción completa

Detalles Bibliográficos
Autores principales: Mishra, Piyush, Dauphinee, Adrian N., Ward, Carl, Sarkar, Sovan, Gunawardena, Arunika H.L.A.N., Manjithaya, Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Basic Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612355/
https://www.ncbi.nlm.nih.gov/pubmed/28792845
http://dx.doi.org/10.1080/15548627.2017.1339002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612355/
https://www.ncbi.nlm.nih.gov/pubmed/28792845
http://dx.doi.org/10.1080/15548627.2017.1339002

Ejemplares similares