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Discovery of pan autophagy inhibitors through a high-throughput screen highlights macroautophagy as an evolutionarily conserved process across 3 eukaryotic kingdoms
Due to the involvement of macroautophagy/autophagy in different pathophysiological conditions such as infections, neurodegeneration and cancer, identification of novel small molecules that modulate the process is of current research and clinical interest. In this work, we developed a luciferase-base...
Autores principales: | Mishra, Piyush, Dauphinee, Adrian N., Ward, Carl, Sarkar, Sovan, Gunawardena, Arunika H.L.A.N., Manjithaya, Ravi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612355/ https://www.ncbi.nlm.nih.gov/pubmed/28792845 http://dx.doi.org/10.1080/15548627.2017.1339002 |
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