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Spontaneous, local diastolic subsarcolemmal calcium releases in single, isolated guinea-pig sinoatrial nodal cells

Uptake and release calcium from the sarcoplasmic reticulum (SR) (dubbed “calcium clock”), in the form of spontaneous, rhythmic, local diastolic calcium releases (LCRs), together with voltage-sensitive ion channels (membrane clock) form a coupled system that regulates the action potential (AP) firing...

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Detalles Bibliográficos
Autores principales:	Sirenko, Syevda G., Yang, Dongmei, Maltseva, Larissa A., Kim, Mary S., Lakatta, Edward G., Maltsev, Victor A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612473/ https://www.ncbi.nlm.nih.gov/pubmed/28945810 http://dx.doi.org/10.1371/journal.pone.0185222

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