Preclinical Evaluation and Monitoring of the Therapeutic Response of a Dual Targeted Hyaluronic Acid Nanodrug

Chemotherapy is a powerful cancer treatment but suffers from poor biocompatibility and a lack of tumor targeting. Here, we developed a CD44-targeted polymeric nanocomplex by encapsulating 10-hydroxycamptothecin (HCPT) into hyaluronic acid nanoparticles (HANP) for targeted cancer therapy. In vitro, t...

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Detalles Bibliográficos
Autores principales: Chen, Minglong, Zhang, Wenqi, Yuan, Kai, Bo, Mingxiang, Chen, Bin, Li, Lu, Ma, Qingjie, Zhu, Lei, Gao, Shi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612705/
https://www.ncbi.nlm.nih.gov/pubmed/29097925
http://dx.doi.org/10.1155/2017/4972701

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