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Estradiol impairs the antiproliferative and proapoptotic effect of Zoledronic acid in hormone sensitive breast cancer cells in vitro

BACKGROUND: Zoledronic acid (ZA) has antiresorptive effects and protects from bone metastasis in women with early breast cancer. In addition, in postmenopausal women with endocrine responsive breast cancer ZA prolongs DFS. The exact mechanism is still unclear. We have therefore investigated the effe...

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Detalles Bibliográficos
Autores principales:	Gschwantler-Kaulich, Daphne, Weingartshofer, Sigrid, Grunt, Thomas W., Mairhofer, Mario, Tan, Yen, Gamper, Jutta, Singer, Christian F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612728/ https://www.ncbi.nlm.nih.gov/pubmed/28945801 http://dx.doi.org/10.1371/journal.pone.0185566

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