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Molecular Imaging of Cancer with Nanoparticle-Based Theranostic Probes
Although advancements in medical technology supporting cancer diagnosis and treatment have improved survival, these technologies still have limitations. Recently, the application of noninvasive imaging for cancer diagnosis and therapy has become an indispensable component in clinical practice. Howev...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612740/ https://www.ncbi.nlm.nih.gov/pubmed/29097909 http://dx.doi.org/10.1155/2017/1026270 |
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author | Ma, Ying-Yu Jin, Ke-Tao Wang, Shi-Bing Wang, Hui-Ju Tong, Xiang-Min Huang, Dong-Sheng Mou, Xiao-Zhou |
author_facet | Ma, Ying-Yu Jin, Ke-Tao Wang, Shi-Bing Wang, Hui-Ju Tong, Xiang-Min Huang, Dong-Sheng Mou, Xiao-Zhou |
author_sort | Ma, Ying-Yu |
collection | PubMed |
description | Although advancements in medical technology supporting cancer diagnosis and treatment have improved survival, these technologies still have limitations. Recently, the application of noninvasive imaging for cancer diagnosis and therapy has become an indispensable component in clinical practice. However, current imaging contrasts and tracers, which are in widespread clinical use, have their intrinsic limitations and disadvantages. Nanotechnologies, which have improved in vivo detection and enhanced targeting efficiency for cancer, may overcome some of the limitations of cancer diagnosis and therapy. Theranostic nanoparticles have great potential as a therapeutic model, which possesses the ability of their nanoplatforms to load targeted molecule for both imaging and therapeutic functions. The resulting nanosystem will likely be critical with the growth of personalized medicine because of their diagnostic potential, effectiveness as a drug delivery vehicle, and ability to oversee patient response to therapy. In this review, we discuss the achievements of modern nanoparticles with the goal of accurate tumor imaging and effective treatment and discuss the future prospects. |
format | Online Article Text |
id | pubmed-5612740 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-56127402017-09-28 Molecular Imaging of Cancer with Nanoparticle-Based Theranostic Probes Ma, Ying-Yu Jin, Ke-Tao Wang, Shi-Bing Wang, Hui-Ju Tong, Xiang-Min Huang, Dong-Sheng Mou, Xiao-Zhou Contrast Media Mol Imaging Review Article Although advancements in medical technology supporting cancer diagnosis and treatment have improved survival, these technologies still have limitations. Recently, the application of noninvasive imaging for cancer diagnosis and therapy has become an indispensable component in clinical practice. However, current imaging contrasts and tracers, which are in widespread clinical use, have their intrinsic limitations and disadvantages. Nanotechnologies, which have improved in vivo detection and enhanced targeting efficiency for cancer, may overcome some of the limitations of cancer diagnosis and therapy. Theranostic nanoparticles have great potential as a therapeutic model, which possesses the ability of their nanoplatforms to load targeted molecule for both imaging and therapeutic functions. The resulting nanosystem will likely be critical with the growth of personalized medicine because of their diagnostic potential, effectiveness as a drug delivery vehicle, and ability to oversee patient response to therapy. In this review, we discuss the achievements of modern nanoparticles with the goal of accurate tumor imaging and effective treatment and discuss the future prospects. Hindawi 2017-06-19 /pmc/articles/PMC5612740/ /pubmed/29097909 http://dx.doi.org/10.1155/2017/1026270 Text en Copyright © 2017 Ying-Yu Ma et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Ma, Ying-Yu Jin, Ke-Tao Wang, Shi-Bing Wang, Hui-Ju Tong, Xiang-Min Huang, Dong-Sheng Mou, Xiao-Zhou Molecular Imaging of Cancer with Nanoparticle-Based Theranostic Probes |
title | Molecular Imaging of Cancer with Nanoparticle-Based Theranostic Probes |
title_full | Molecular Imaging of Cancer with Nanoparticle-Based Theranostic Probes |
title_fullStr | Molecular Imaging of Cancer with Nanoparticle-Based Theranostic Probes |
title_full_unstemmed | Molecular Imaging of Cancer with Nanoparticle-Based Theranostic Probes |
title_short | Molecular Imaging of Cancer with Nanoparticle-Based Theranostic Probes |
title_sort | molecular imaging of cancer with nanoparticle-based theranostic probes |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612740/ https://www.ncbi.nlm.nih.gov/pubmed/29097909 http://dx.doi.org/10.1155/2017/1026270 |
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