Increased liver AGEs induce hepatic injury mediated through an OST48 pathway

The protein oligosaccharyltransferase-48 (OST48) is integral to protein N-glycosylation in the endoplasmic reticulum (ER) but is also postulated to act as a membrane localised clearance receptor for advanced glycation end-products (AGE). Hepatic ER stress and AGE accumulation are each implicated in...

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Detalles Bibliográficos
Autores principales: Zhuang, Aowen, Yap, Felicia YT., Bruce, Clinton, Leung, Chris, Plan, Manuel R., Sullivan, Mitchell A., Herath, Chandana, McCarthy, Domenica, Sourris, Karly C., Kantharidis, Phillip, Coughlan, Melinda T., Febbraio, Mark A., Hodson, Mark P., Watt, Matthew J., Angus, Peter, Schulz, Benjamin L., Forbes, Josephine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612946/
https://www.ncbi.nlm.nih.gov/pubmed/28947796
http://dx.doi.org/10.1038/s41598-017-12548-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612946/
https://www.ncbi.nlm.nih.gov/pubmed/28947796
http://dx.doi.org/10.1038/s41598-017-12548-4

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