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Resolving distinct molecular origins for copper effects on PAI-1
Components of the fibrinolytic system are subjected to stringent control to maintain proper hemostasis. Central to this regulation is the serpin plasminogen activator inhibitor-1 (PAI-1), which is responsible for specific and rapid inhibition of fibrinolytic proteases. Active PAI-1 is inherently uns...
Autores principales: | Bucci, Joel C., McClintock, Carlee S., Chu, Yuzhuo, Ware, Gregory L., McConnell, Kayla D., Emerson, Joseph P., Peterson, Cynthia B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613068/ https://www.ncbi.nlm.nih.gov/pubmed/28913669 http://dx.doi.org/10.1007/s00775-017-1489-5 |
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