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Functional Changes in the Gut Microbiome Contribute to Transforming Growth Factor β-Deficient Colon Cancer

Colorectal cancer (CRC) is one of the most treatable cancers, with a 5-year survival rate of ~64%, yet over 50,000 deaths occur yearly in the United States. In 15% of cases, deficiency in mismatch repair leads to null mutations in transforming growth factor β (TGF-β) type II receptor, yet genotype a...

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Detalles Bibliográficos
Autores principales:	Daniel, Scott G., Ball, Corbie L., Besselsen, David G., Doetschman, Tom, Hurwitz, Bonnie L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613170/ https://www.ncbi.nlm.nih.gov/pubmed/28951889 http://dx.doi.org/10.1128/mSystems.00065-17

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