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TLR4 antagonist suppresses airway remodeling in asthma by inhibiting the T-helper 2 response

Airway remodeling is a hallmark of bronchial asthma. Our group has previously reported that the thymic stromal lymphopoietin (TSLP), an airway epithelial-derived cytokine, has a central role in the pathogenesis of airway remodeling, and that toll-like receptor (TLR) 4 signaling in epithelial cells m...

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Detalles Bibliográficos
Autores principales: Li, Ming, Wang, Zhao-Ni, Yang, Li-Fen, Yan, Yan, Cai, Liang-Ming, Li, Ya-Ting, Qiao, Yong-Kang, Chen, Zhuang-Gui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613182/
https://www.ncbi.nlm.nih.gov/pubmed/28966674
http://dx.doi.org/10.3892/etm.2017.4898