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Biphasic and directed translocation of protein kinase Cα inside cultured endothelial cells before migration

Mechanical wounding of an endothelial monolayer induces an immediate Ca(2+) wave. Several hours later, the denuded area is covered by endothelial cells (ECs) that migrate to the wound. This migration process is closely related to protein kinase Cα (PKCα), a Ca(2+)-dependent protein that translocates...

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Detalles Bibliográficos
Autores principales: Arai, Masataka, Shimada, Tomoya, Kora, Chihiro, Nakashima, Kazuhiro, Sera, Toshihiro, Kudo, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613218/
https://www.ncbi.nlm.nih.gov/pubmed/28955796
http://dx.doi.org/10.1016/j.bbrep.2017.08.003