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Biphasic and directed translocation of protein kinase Cα inside cultured endothelial cells before migration
Mechanical wounding of an endothelial monolayer induces an immediate Ca(2+) wave. Several hours later, the denuded area is covered by endothelial cells (ECs) that migrate to the wound. This migration process is closely related to protein kinase Cα (PKCα), a Ca(2+)-dependent protein that translocates...
Autores principales: | Arai, Masataka, Shimada, Tomoya, Kora, Chihiro, Nakashima, Kazuhiro, Sera, Toshihiro, Kudo, Susumu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613218/ https://www.ncbi.nlm.nih.gov/pubmed/28955796 http://dx.doi.org/10.1016/j.bbrep.2017.08.003 |
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