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STAT3 and NF-κB are common targets for kaempferol-mediated attenuation of COX-2 expression in IL-6-induced macrophages and carrageenan-induced mouse paw edema

Cycloxygenase-2 (COX-2) is the inducible isoform of cycloxygenase enzyme family that catalyzes synthesis of inflammatory mediators, prostanoids and prostaglandins, and therefore, can be targeted by anti-inflammatory drugs. Here, we showed a plant polyphenol, kaempferol, attenuated IL-6-induced COX-2...

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Detalles Bibliográficos
Autores principales:	Basu, Anandita, Das, Anindhya Sundar, Sharma, Manoj, Pathak, Manash Pratim, Chattopadhyay, Pronobesh, Biswas, Kaushik, Mukhopadhyay, Rupak
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613220/ https://www.ncbi.nlm.nih.gov/pubmed/28955792 http://dx.doi.org/10.1016/j.bbrep.2017.08.005

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