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Understanding co-polymerization in amyloid formation by direct observation of mixed oligomers

Although amyloid assembly in vitro is commonly investigated using single protein sequences, fibril formation in vivo can be more heterogeneous, involving co-assembly of proteins of different length, sequence and/or post-translational modifications. Emerging evidence suggests that co-polymerization c...

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Detalles Bibliográficos
Autores principales:	Young, Lydia M., Tu, Ling-Hsien, Raleigh, Daniel P., Ashcroft, Alison E., Radford, Sheena E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2017
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613229/ https://www.ncbi.nlm.nih.gov/pubmed/28970890 http://dx.doi.org/10.1039/c7sc00620a

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