Procalcitonin for the diagnosis of invasive candidiasis: what is the evidence?

Procalcitonin is a widely used marker for the evaluation of infection and sepsis and to guide antibiotic therapy. During the last decade, several studies evaluated its role and diagnostic performance as a surrogate marker for the identification of Candida spp. in suspected invasive candidiasis. A lo...

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Autores principales: Raineri, Santi Maurizio, Cortegiani, Andrea, Vitale, Filippo, Iozzo, Pasquale, Giarratano, Antonino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613326/
https://www.ncbi.nlm.nih.gov/pubmed/28975031
http://dx.doi.org/10.1186/s40560-017-0252-x
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author Raineri, Santi Maurizio
Cortegiani, Andrea
Vitale, Filippo
Iozzo, Pasquale
Giarratano, Antonino
author_facet Raineri, Santi Maurizio
Cortegiani, Andrea
Vitale, Filippo
Iozzo, Pasquale
Giarratano, Antonino
author_sort Raineri, Santi Maurizio
collection PubMed
description Procalcitonin is a widely used marker for the evaluation of infection and sepsis and to guide antibiotic therapy. During the last decade, several studies evaluated its role and diagnostic performance as a surrogate marker for the identification of Candida spp. in suspected invasive candidiasis. A low serum level and a favorable negative predictive value are the main findings for procalcitonin in this setting. The aim of this report is to provide an updated brief summary of the evidence supporting the use of PCT for the management of invasive candidiasis.
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spelling pubmed-56133262017-10-03 Procalcitonin for the diagnosis of invasive candidiasis: what is the evidence? Raineri, Santi Maurizio Cortegiani, Andrea Vitale, Filippo Iozzo, Pasquale Giarratano, Antonino J Intensive Care Letter to the Editor Procalcitonin is a widely used marker for the evaluation of infection and sepsis and to guide antibiotic therapy. During the last decade, several studies evaluated its role and diagnostic performance as a surrogate marker for the identification of Candida spp. in suspected invasive candidiasis. A low serum level and a favorable negative predictive value are the main findings for procalcitonin in this setting. The aim of this report is to provide an updated brief summary of the evidence supporting the use of PCT for the management of invasive candidiasis. BioMed Central 2017-09-25 /pmc/articles/PMC5613326/ /pubmed/28975031 http://dx.doi.org/10.1186/s40560-017-0252-x Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Letter to the Editor
Raineri, Santi Maurizio
Cortegiani, Andrea
Vitale, Filippo
Iozzo, Pasquale
Giarratano, Antonino
Procalcitonin for the diagnosis of invasive candidiasis: what is the evidence?
title Procalcitonin for the diagnosis of invasive candidiasis: what is the evidence?
title_full Procalcitonin for the diagnosis of invasive candidiasis: what is the evidence?
title_fullStr Procalcitonin for the diagnosis of invasive candidiasis: what is the evidence?
title_full_unstemmed Procalcitonin for the diagnosis of invasive candidiasis: what is the evidence?
title_short Procalcitonin for the diagnosis of invasive candidiasis: what is the evidence?
title_sort procalcitonin for the diagnosis of invasive candidiasis: what is the evidence?
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613326/
https://www.ncbi.nlm.nih.gov/pubmed/28975031
http://dx.doi.org/10.1186/s40560-017-0252-x
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