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Repeated lipopolysaccharide exposure causes corticosteroid insensitive airway inflammation via activation of phosphoinositide-3-kinase δ pathway

Corticosteroid resistance is one of major barriers to effective management of chronic inflammatory respiratory diseases, such as chronic obstructive pulmonary disease (COPD) and severe asthma. These patients often experience exacerbations with viral and/or bacterial infection, which may cause contin...

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Detalles Bibliográficos
Autores principales:	Ueda, Keitaro, Nishimoto, Yuki, Kimura, Genki, Masuko, Takashi, Barnes, Peter J., Ito, Kazuhiro, Kizawa, Yasuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613638/ https://www.ncbi.nlm.nih.gov/pubmed/28955927 http://dx.doi.org/10.1016/j.bbrep.2016.07.020

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