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Observation of Blood Donor-Recipient Malaria Parasitaemia Patterns in a Malaria Endemic Region
BACKGROUND: Asymptomatic malaria parasitaemia has been documented in donor blood in West Africa. However, donated blood is not routinely screened for malaria parasites (MPs). The present study therefore aimed to document the frequency of blood transfusion-induced donor-recipient malaria parasitaemia...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613642/ https://www.ncbi.nlm.nih.gov/pubmed/29138642 http://dx.doi.org/10.1155/2017/7149261 |
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author | Faruk, Jamilu Abdullahi Ogunrinde, Gboye Olufemi Mamman, Aisha Indo |
author_facet | Faruk, Jamilu Abdullahi Ogunrinde, Gboye Olufemi Mamman, Aisha Indo |
author_sort | Faruk, Jamilu Abdullahi |
collection | PubMed |
description | BACKGROUND: Asymptomatic malaria parasitaemia has been documented in donor blood in West Africa. However, donated blood is not routinely screened for malaria parasites (MPs). The present study therefore aimed to document the frequency of blood transfusion-induced donor-recipient malaria parasitaemia patterns, in children receiving blood transfusion in a tertiary health-centre. METHODOLOGY: A cross-sectional, observational study involving 140 children receiving blood transfusion was carried out. Blood donor units and patients' blood samples were obtained, for the determination of malaria parasites (MPs). Giemsa staining technique was used to determine the presence of malaria parasitaemia. RESULTS: Malaria parasites were detected in 7% of donor blood and in 8.3% of the recipients' pretransfusion blood. The incidence of posttransfusion MPs was 3%, but none of these were consistent with blood transfusion-induced malaria, as no child with posttransfusion parasitaemia was transfused with parasitized donor blood. Majority of the blood transfusions (89.4%) had no MPs in either donors or recipients, while 6.8% had MPs in both donors and recipients, with the remaining 3.8% showing MPs in recipients alone. CONCLUSION: In conclusion, the incidence of posttransfusion malaria parasitaemia appears low under the prevailing circumstances. |
format | Online Article Text |
id | pubmed-5613642 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-56136422017-11-14 Observation of Blood Donor-Recipient Malaria Parasitaemia Patterns in a Malaria Endemic Region Faruk, Jamilu Abdullahi Ogunrinde, Gboye Olufemi Mamman, Aisha Indo J Trop Med Research Article BACKGROUND: Asymptomatic malaria parasitaemia has been documented in donor blood in West Africa. However, donated blood is not routinely screened for malaria parasites (MPs). The present study therefore aimed to document the frequency of blood transfusion-induced donor-recipient malaria parasitaemia patterns, in children receiving blood transfusion in a tertiary health-centre. METHODOLOGY: A cross-sectional, observational study involving 140 children receiving blood transfusion was carried out. Blood donor units and patients' blood samples were obtained, for the determination of malaria parasites (MPs). Giemsa staining technique was used to determine the presence of malaria parasitaemia. RESULTS: Malaria parasites were detected in 7% of donor blood and in 8.3% of the recipients' pretransfusion blood. The incidence of posttransfusion MPs was 3%, but none of these were consistent with blood transfusion-induced malaria, as no child with posttransfusion parasitaemia was transfused with parasitized donor blood. Majority of the blood transfusions (89.4%) had no MPs in either donors or recipients, while 6.8% had MPs in both donors and recipients, with the remaining 3.8% showing MPs in recipients alone. CONCLUSION: In conclusion, the incidence of posttransfusion malaria parasitaemia appears low under the prevailing circumstances. Hindawi 2017 2017-08-24 /pmc/articles/PMC5613642/ /pubmed/29138642 http://dx.doi.org/10.1155/2017/7149261 Text en Copyright © 2017 Jamilu Abdullahi Faruk et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Faruk, Jamilu Abdullahi Ogunrinde, Gboye Olufemi Mamman, Aisha Indo Observation of Blood Donor-Recipient Malaria Parasitaemia Patterns in a Malaria Endemic Region |
title | Observation of Blood Donor-Recipient Malaria Parasitaemia Patterns in a Malaria Endemic Region |
title_full | Observation of Blood Donor-Recipient Malaria Parasitaemia Patterns in a Malaria Endemic Region |
title_fullStr | Observation of Blood Donor-Recipient Malaria Parasitaemia Patterns in a Malaria Endemic Region |
title_full_unstemmed | Observation of Blood Donor-Recipient Malaria Parasitaemia Patterns in a Malaria Endemic Region |
title_short | Observation of Blood Donor-Recipient Malaria Parasitaemia Patterns in a Malaria Endemic Region |
title_sort | observation of blood donor-recipient malaria parasitaemia patterns in a malaria endemic region |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613642/ https://www.ncbi.nlm.nih.gov/pubmed/29138642 http://dx.doi.org/10.1155/2017/7149261 |
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