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Uncontrolled Hypertension Increases with Age in an Older Community-Dwelling Chinese Population in Shanghai

We determined the prevalence of hypertension, medication usage and attainment of blood pressure goals in older (≥65 to <80 years and ≥80 years) urban community-dwelling Chinese subjects. Data were obtained in 3950 subjects (mean age 72.0 years, 1745 male) including 609 subjects aged ≥80 years in...

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Autores principales: Peng, Sheng, Shen, Ting, Liu, Jie, Tomlinson, Brian, Sun, Huimin, Chen, Xiaoli, Chan, Paul, Kuang, YaShu, Zheng, Liang, Wu, Hong, Ding, Xugang, Qian, Dingguang, Shen, Yixin, Gao, Pingjin, Fan, Huimin, Liu, Zhongmin, Zhang, Yuzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614321/
https://www.ncbi.nlm.nih.gov/pubmed/28966801
http://dx.doi.org/10.14336/AD.2016.1220
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author Peng, Sheng
Shen, Ting
Liu, Jie
Tomlinson, Brian
Sun, Huimin
Chen, Xiaoli
Chan, Paul
Kuang, YaShu
Zheng, Liang
Wu, Hong
Ding, Xugang
Qian, Dingguang
Shen, Yixin
Gao, Pingjin
Fan, Huimin
Liu, Zhongmin
Zhang, Yuzhen
author_facet Peng, Sheng
Shen, Ting
Liu, Jie
Tomlinson, Brian
Sun, Huimin
Chen, Xiaoli
Chan, Paul
Kuang, YaShu
Zheng, Liang
Wu, Hong
Ding, Xugang
Qian, Dingguang
Shen, Yixin
Gao, Pingjin
Fan, Huimin
Liu, Zhongmin
Zhang, Yuzhen
author_sort Peng, Sheng
collection PubMed
description We determined the prevalence of hypertension, medication usage and attainment of blood pressure goals in older (≥65 to <80 years and ≥80 years) urban community-dwelling Chinese subjects. Data were obtained in 3950 subjects (mean age 72.0 years, 1745 male) including 609 subjects aged ≥80 years in the Shanghai Elderly Cardiovascular Health Study (SHECHS). Established cardiovascular disease was present in 7.7% of participants. The prevalence of hypertension was 74.8% overall and it was more than 80% in individuals considered to be in moderate and higher cardiovascular disease risk categories. In hypertensive subjects, 67.1% were on treatment and treatment was more frequent in high and very high cardiovascular risk individuals. Attainment of the systolic blood pressure goal <150 mmHg was 62.9% and was greater in the ≥65 to <80 years group than in the ≥80 years group. The most commonly used antihypertensive treatments were calcium channel blockers (54.2%), followed by angiotensin receptor blockers (43.1%). Diuretics were used in 2.6%. Fixed-dose combination antihypertensive tablets were used in some of the ≥65 to <80 years group (12.4%) and more of the ≥80 years group (18.2%) and 70.9% of the ≥65 to <80 years group and 80.2% of the ≥80 years group were on monotherapy. There were high prevalence and high treatment rates of hypertension, but poor attainment of the systolic blood pressure goal of <150 mmHg, especially in the ≥80 years group of community-dwelling Chinese. Considering that more intensive treatment of hypertension in older subjects may be warranted after recent studies, this might be achieved by more frequent use of combinations of effective therapies and diuretics.
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spelling pubmed-56143212017-10-01 Uncontrolled Hypertension Increases with Age in an Older Community-Dwelling Chinese Population in Shanghai Peng, Sheng Shen, Ting Liu, Jie Tomlinson, Brian Sun, Huimin Chen, Xiaoli Chan, Paul Kuang, YaShu Zheng, Liang Wu, Hong Ding, Xugang Qian, Dingguang Shen, Yixin Gao, Pingjin Fan, Huimin Liu, Zhongmin Zhang, Yuzhen Aging Dis Original Article We determined the prevalence of hypertension, medication usage and attainment of blood pressure goals in older (≥65 to <80 years and ≥80 years) urban community-dwelling Chinese subjects. Data were obtained in 3950 subjects (mean age 72.0 years, 1745 male) including 609 subjects aged ≥80 years in the Shanghai Elderly Cardiovascular Health Study (SHECHS). Established cardiovascular disease was present in 7.7% of participants. The prevalence of hypertension was 74.8% overall and it was more than 80% in individuals considered to be in moderate and higher cardiovascular disease risk categories. In hypertensive subjects, 67.1% were on treatment and treatment was more frequent in high and very high cardiovascular risk individuals. Attainment of the systolic blood pressure goal <150 mmHg was 62.9% and was greater in the ≥65 to <80 years group than in the ≥80 years group. The most commonly used antihypertensive treatments were calcium channel blockers (54.2%), followed by angiotensin receptor blockers (43.1%). Diuretics were used in 2.6%. Fixed-dose combination antihypertensive tablets were used in some of the ≥65 to <80 years group (12.4%) and more of the ≥80 years group (18.2%) and 70.9% of the ≥65 to <80 years group and 80.2% of the ≥80 years group were on monotherapy. There were high prevalence and high treatment rates of hypertension, but poor attainment of the systolic blood pressure goal of <150 mmHg, especially in the ≥80 years group of community-dwelling Chinese. Considering that more intensive treatment of hypertension in older subjects may be warranted after recent studies, this might be achieved by more frequent use of combinations of effective therapies and diuretics. JKL International LLC 2017-10-01 /pmc/articles/PMC5614321/ /pubmed/28966801 http://dx.doi.org/10.14336/AD.2016.1220 Text en Copyright: © 2017 Peng et al. http://creativecommons.org/licenses/by/2.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.
spellingShingle Original Article
Peng, Sheng
Shen, Ting
Liu, Jie
Tomlinson, Brian
Sun, Huimin
Chen, Xiaoli
Chan, Paul
Kuang, YaShu
Zheng, Liang
Wu, Hong
Ding, Xugang
Qian, Dingguang
Shen, Yixin
Gao, Pingjin
Fan, Huimin
Liu, Zhongmin
Zhang, Yuzhen
Uncontrolled Hypertension Increases with Age in an Older Community-Dwelling Chinese Population in Shanghai
title Uncontrolled Hypertension Increases with Age in an Older Community-Dwelling Chinese Population in Shanghai
title_full Uncontrolled Hypertension Increases with Age in an Older Community-Dwelling Chinese Population in Shanghai
title_fullStr Uncontrolled Hypertension Increases with Age in an Older Community-Dwelling Chinese Population in Shanghai
title_full_unstemmed Uncontrolled Hypertension Increases with Age in an Older Community-Dwelling Chinese Population in Shanghai
title_short Uncontrolled Hypertension Increases with Age in an Older Community-Dwelling Chinese Population in Shanghai
title_sort uncontrolled hypertension increases with age in an older community-dwelling chinese population in shanghai
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614321/
https://www.ncbi.nlm.nih.gov/pubmed/28966801
http://dx.doi.org/10.14336/AD.2016.1220
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