Age-related Impairment of Vascular Structure and Functions

Among age-related diseases, cardiovascular and cerebrovascular diseases are major causes of death. Vascular dysfunction is a key characteristic of these diseases wherein age is an independent and essential risk factor. The present work will review morphological alterations of aging vessels in-depth,...

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Detalles Bibliográficos
Autores principales: Xu, Xianglai, Wang, Brian, Ren, Changhong, Hu, Jiangnan, Greenberg, David A., Chen, Tianxiang, Xie, Liping, Jin, Kunlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614324/
https://www.ncbi.nlm.nih.gov/pubmed/28966804
http://dx.doi.org/10.14336/AD.2017.0430
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author Xu, Xianglai
Wang, Brian
Ren, Changhong
Hu, Jiangnan
Greenberg, David A.
Chen, Tianxiang
Xie, Liping
Jin, Kunlin
author_facet Xu, Xianglai
Wang, Brian
Ren, Changhong
Hu, Jiangnan
Greenberg, David A.
Chen, Tianxiang
Xie, Liping
Jin, Kunlin
author_sort Xu, Xianglai
collection PubMed
description Among age-related diseases, cardiovascular and cerebrovascular diseases are major causes of death. Vascular dysfunction is a key characteristic of these diseases wherein age is an independent and essential risk factor. The present work will review morphological alterations of aging vessels in-depth, which includes the discussion of age-related microvessel loss and changes to vasculature involving the capillary basement membrane, intima, media, and adventitia as well as the accompanying vascular dysfunctions arising from these alterations.
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spelling pubmed-56143242017-10-01 Age-related Impairment of Vascular Structure and Functions Xu, Xianglai Wang, Brian Ren, Changhong Hu, Jiangnan Greenberg, David A. Chen, Tianxiang Xie, Liping Jin, Kunlin Aging Dis Review Among age-related diseases, cardiovascular and cerebrovascular diseases are major causes of death. Vascular dysfunction is a key characteristic of these diseases wherein age is an independent and essential risk factor. The present work will review morphological alterations of aging vessels in-depth, which includes the discussion of age-related microvessel loss and changes to vasculature involving the capillary basement membrane, intima, media, and adventitia as well as the accompanying vascular dysfunctions arising from these alterations. JKL International LLC 2017-10-01 /pmc/articles/PMC5614324/ /pubmed/28966804 http://dx.doi.org/10.14336/AD.2017.0430 Text en Copyright: © 2017 Xu et al. http://creativecommons.org/licenses/by/2.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.
spellingShingle Review
Xu, Xianglai
Wang, Brian
Ren, Changhong
Hu, Jiangnan
Greenberg, David A.
Chen, Tianxiang
Xie, Liping
Jin, Kunlin
Age-related Impairment of Vascular Structure and Functions
title Age-related Impairment of Vascular Structure and Functions
title_full Age-related Impairment of Vascular Structure and Functions
title_fullStr Age-related Impairment of Vascular Structure and Functions
title_full_unstemmed Age-related Impairment of Vascular Structure and Functions
title_short Age-related Impairment of Vascular Structure and Functions
title_sort age-related impairment of vascular structure and functions
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614324/
https://www.ncbi.nlm.nih.gov/pubmed/28966804
http://dx.doi.org/10.14336/AD.2017.0430
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