Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4

While it is recognized that aquaporin-4 (AQP4)-specific T cells and antibodies participate in the pathogenesis of neuromyelitis optica (NMO), a human central nervous system (CNS) autoimmune demyelinating disease, creation of an AQP4-targeted model with both clinical and histologic manifestations of...

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Detalles Bibliográficos
Autores principales: Sagan, Sharon A., Cruz-Herranz, Andrés, Spencer, Collin M., Ho, Peggy P., Steinman, Lawrence, Green, Ari J., Sobel, Raymond A., Zamvil, Scott S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614352/
https://www.ncbi.nlm.nih.gov/pubmed/28872108
http://dx.doi.org/10.3791/56185

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