Cargando…

Therapeutic potential of GW501516 and the role of Peroxisome proliferator-activated receptor β/δ and B-cell lymphoma 6 in inflammatory signaling in human pancreatic cancer cells

Peroxisome proliferator-activated receptor β/δ (PPARβ/δ) is a member of the nuclear receptor superfamily and a ligand-activated transcription factor that is involved in the regulation of the inflammatory response via activation of anti-inflammatory target genes and ligand-induced disassociation with...

Descripción completa

Detalles Bibliográficos
Autores principales:	Smith, Russell W., Coleman, Jeffrey D., Thompson, Jerry T., Vanden Heuvel, John P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614479/ https://www.ncbi.nlm.nih.gov/pubmed/28955982 http://dx.doi.org/10.1016/j.bbrep.2016.10.014

Ejemplares similares

Role of Peroxisome Proliferator-Activated Receptor β/δ and B-Cell Lymphoma-6 in Regulation of Genes Involved in Metastasis and Migration in Pancreatic Cancer Cells
por: Coleman, Jeffrey D., et al.
Publicado: (2013)

The Role of PPARδ Agosnist GW501516 in Rats with Gestational Diabetes Mellitus
por: Zhou, Jun, et al.
Publicado: (2020)

The PPARδ Ligand GW501516 Reduces Growth but Not Apoptosis in Mouse Inner Medullary Collecting Duct Cells
por: Clark, Jordan, et al.
Publicado: (2009)

A metabolomic study of the PPARδ agonist GW501516 for enhancing running endurance in Kunming mice
por: Chen, Wei, et al.
Publicado: (2015)

GW501516-activated PPARβ/δ promotes liver fibrosis via p38-JNK MAPK-induced hepatic stellate cell proliferation
por: Kostadinova, Radina, et al.
Publicado: (2012)

PPARβ/δ Agonist GW501516 Inhibits Tumorigenicity of Undifferentiated Nasopharyngeal Carcinoma in C666-1 Cells by Promoting Apoptosis
por: Ji, Yangyang, et al.
Publicado: (2018)

PPARδ Agonist GW501516 Inhibits PDGF-Stimulated Pulmonary Arterial Smooth Muscle Cell Function Related to Pathological Vascular Remodeling
por: Liu, Guangjie, et al.
Publicado: (2013)

PPARδ Agonist GW501516 Suppresses the TGF-β-Induced Profibrotic Response of Human Bronchial Fibroblasts from Asthmatic Patients
por: Paw, Milena, et al.
Publicado: (2023)

GW501516, a PPAR-BETA/DELTA agonist, improves inflammatory pathways in the kidney of high-fructose fed mice
por: Magliano, D'Angelo Carlo, et al.
Publicado: (2015)

PPARβ/δ Agonist GW501516 Inhibits Tumorigenesis and Promotes Apoptosis of the Undifferentiated Nasopharyngeal Carcinoma C666-1 Cells by Regulating miR-206
por: Gu, Linglan, et al.
Publicado: (2019)

The PPARδ Agonist GW501516 Improves Lipolytic/Lipogenic Balance through CPT1 and PEPCK during the Development of Pre-Implantation Bovine Embryos
por: Idrees, Muhammad, et al.
Publicado: (2019)

Effects of the PPAR-β agonist GW501516 in an in vitro model of brain inflammation and antibody-induced demyelination
por: Defaux, Antoinette, et al.
Publicado: (2009)

Molecular and nanoscale evaluation of N-cadherin expression in invasive bladder cancer cells under control conditions or GW501516 exposure
por: Elie-Caille, Céline, et al.
Publicado: (2020)

GW501516, a PPARδ Agonist, Ameliorates Tubulointerstitial Inflammation in Proteinuric Kidney Disease via Inhibition of TAK1-NFκB Pathway in Mice
por: Yang, Xu, et al.
Publicado: (2011)

PPARβ/δ Agonism with GW501516 Increases Myotube PGC-1α Content and Reduces BCAA Media Content Independent of Changes in BCAA Catabolic Enzyme Expression
por: Rivera, Caroline N., et al.
Publicado: (2023)

Examination of Ligand-Dependent Coactivator Recruitment by Peroxisome Proliferator-Activated Receptor-α (PPARα)
por: Tien, Eric S., et al.
Publicado: (2006)

Regulation of Peroxisome Proliferator-Activated Receptors by E6-Associated Protein
por: Gopinathan, Lakshmi, et al.
Publicado: (2008)

Targeting Peroxisome Proliferator-Activated Receptor-β/δ (PPARβ/δ) for Cancer Chemoprevention
por: Peters, Jeffrey M., et al.
Publicado: (2015)

The Role of Peroxisome Proliferator-Activated Receptor β/δ on the Inflammatory Basis of Metabolic Disease
por: Coll, Teresa, et al.
Publicado: (2010)

Peroxisome proliferator-activated receptor δ agonist attenuates hepatic steatosis by anti-inflammatory mechanism
por: Lee, Mi Young, et al.
Publicado: (2012)

Unraveling the role of peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) expression in colon carcinogenesis
por: Peters, Jeffrey M., et al.
Publicado: (2019)

Ligand-Activated Peroxisome Proliferator-Activated Receptor β/δ Facilitates Cell Proliferation in Human Cholesteatoma Keratinocytes
por: Zhang, Chen, et al.
Publicado: (2020)

Cadmium Toxicity Is Regulated by Peroxisome Proliferator-Activated Receptor δ in Human Proximal Tubular Cells
por: Mori, Chikage, et al.
Publicado: (2022)

Peroxisome Proliferator-Activated Receptor β/δ in the Brain: Facts and Hypothesis
por: Hall, M. G., et al.
Publicado: (2008)

The peroxisome proliferator activated receptor δ is required for the differentiation of THP-1 monocytic cells by phorbol ester
por: Vosper, Helen, et al.
Publicado: (2003)

Metabolic Functions of Peroxisome Proliferator-Activated Receptor β/δ in Skeletal Muscle
por: Gaudel, Céline, et al.
Publicado: (2007)

Induction of Metastatic Gastric Cancer by Peroxisome Proliferator-Activated Receptorδ Activation
por: Pollock, Claire B., et al.
Publicado: (2010)

Peroxisomal Proliferator-Activated Receptor β/δ Deficiency Induces Cognitive Alterations
por: Espinosa-Jiménez, Triana, et al.
Publicado: (2022)

Treatment of VLCAD-Deficient Patient Fibroblasts with Peroxisome Proliferator-Activated Receptor δ Agonist Improves Cellular Bioenergetics
por: D’Annibale, Olivia M., et al.
Publicado: (2022)

MicroRNA-9 regulates the expression of peroxisome proliferator-activated receptor δ in human monocytes during the inflammatory response
por: THULIN, PETRA, et al.
Publicado: (2013)

Unraveling the Role of Peroxisome Proliferator-Activated Receptor β/Δ (PPAR β/Δ) in Angiogenesis Associated with Multiple Myeloma
por: Leone, Patrizia, et al.
Publicado: (2023)

GW Stewart
por: Kilmer, Misha E, et al.
Publicado: (2010)

The Potential Applications of Peroxisome Proliferator-Activated Receptor δ Ligands in Assisted Reproductive Technology
por: Huang, Jaou-Chen
Publicado: (2008)

Analysis of the peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) cistrome reveals novel co-regulatory role of ATF4
por: Khozoie, Combiz, et al.
Publicado: (2012)

Effects of the PPAR-β/δ agonist GW0742 during resuscitated porcine septic shock
por: Wepler, Martin, et al.
Publicado: (2013)

Activation of Peroxisome Proliferator–Activated Receptor δ Inhibits Streptozotocin-Induced Diabetic Nephropathy Through Anti-Inflammatory Mechanisms in Mice
por: Matsushita, Yuichi, et al.
Publicado: (2011)

Increased hepatic oxidative metabolism distinguishes the action of Peroxisome proliferator-activated receptor δ from Peroxisome proliferator-activated receptor γ in the ob/ob mouse
por: Roberts, Lee D, et al.
Publicado: (2009)

Inhibition of testicular embryonal carcinoma cell tumorigenicity by peroxisome proliferator-activated receptor-β/δ- and retinoic acid receptor-dependent mechanisms
por: Yao, Pei-Li, et al.
Publicado: (2015)

Peroxisome Proliferator-Activated Receptor Delta Agonist (PPAR- δ) and Selective Androgen Receptor Modulator (SARM) Abuse: Clinical, Analytical and Biological Data in a Case Involving a Poisonous Combination of GW1516 (Cardarine) and MK2866 (Ostarine)
por: Kintz, Pascal, et al.
Publicado: (2021)

Genomewide Analyses Define Different Modes of Transcriptional Regulation by Peroxisome Proliferator-Activated Receptor-β/δ (PPARβ/δ)
por: Adhikary, Till, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_du2opvegc9vhj8q9famdha78o3