Tumor-Associated Macrophages Suppress the Cytotoxic Activity of Antimitotic Agents

Antimitotic agents, including Taxol, disrupt microtubule dynamics and cause a protracted mitotic arrest and subsequent cell death. Despite the broad utility of these drugs in breast cancer and other tumor types, clinical response remains variable. Tumor-associated macrophages (TAMs) suppress the dur...

Descripción completa

Detalles Bibliográficos
Autores principales: Olson, Oakley C., Kim, Hyunjung, Quail, Daniela F., Foley, Emily A., Joyce, Johanna A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614506/
https://www.ncbi.nlm.nih.gov/pubmed/28380350
http://dx.doi.org/10.1016/j.celrep.2017.03.038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614506/
https://www.ncbi.nlm.nih.gov/pubmed/28380350
http://dx.doi.org/10.1016/j.celrep.2017.03.038

Ejemplares similares