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Tumor-Associated Macrophages Suppress the Cytotoxic Activity of Antimitotic Agents
Antimitotic agents, including Taxol, disrupt microtubule dynamics and cause a protracted mitotic arrest and subsequent cell death. Despite the broad utility of these drugs in breast cancer and other tumor types, clinical response remains variable. Tumor-associated macrophages (TAMs) suppress the dur...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614506/ https://www.ncbi.nlm.nih.gov/pubmed/28380350 http://dx.doi.org/10.1016/j.celrep.2017.03.038 |