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Synergistic effects of 15-deoxy Δ(12,14)-prostaglandin J(2) on the anti-tumor activity of doxorubicin in renal cell carcinoma

An endogenous anticancer agent, 15-deoxy -Δ(12,14)-prostaglandin J(2) (15d-PGJ(2)) induces apoptosis in the chemoresistant renal cell carcinoma (RCC). Peroxisome proliferator-activated receptor-γ (PPARγ) is a nuclear receptor for 15d-PGJ(2), and mediates the cytotoxicity of 15d-PGJ(2) in many cancer...

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Detalles Bibliográficos
Autores principales:	Yamamoto, Yasuhiro, Yamamoto, Takehiro, Koma, Hiromi, Nishii, Ayaka, Yagami, Tatsurou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614541/ https://www.ncbi.nlm.nih.gov/pubmed/28955990 http://dx.doi.org/10.1016/j.bbrep.2016.11.004

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