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De novo protein sequencing, humanization and in vitro effects of an antihuman CD34 mouse monoclonal antibody

QBEND/10 is a mouse immunoglobulin lambda-chain monoclonal antibody with strict specificity against human hematopoietic progenitor cell antigen CD34. Our in vitro study showed that QBEND/10 impairs the tube formation of human umbilical vein endothelial cells (HUVECs), suggesting that the antibody ma...

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Detalles Bibliográficos
Autores principales:	Fan, Chia-Yu, Huang, Sheng-Yu, Chou, Min-Yuan, Lyu, Ping-Chiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614552/ https://www.ncbi.nlm.nih.gov/pubmed/28955989 http://dx.doi.org/10.1016/j.bbrep.2016.11.006

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