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Natural mismatch repair mutations mediate phenotypic diversity and drug resistance in Cryptococcus deuterogattii

Pathogenic microbes confront an evolutionary conflict between the pressure to maintain genome stability and the need to adapt to mounting external stresses. Bacteria often respond with elevated mutation rates, but little evidence exists of stable eukaryotic hypermutators in nature. Whole genome rese...

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Detalles Bibliográficos
Autores principales:	Billmyre, R Blake, Clancey, Shelly Applen, Heitman, Joseph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2017
Materias:	Microbiology and Infectious Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614558/ https://www.ncbi.nlm.nih.gov/pubmed/28948913 http://dx.doi.org/10.7554/eLife.28802

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