Protease activity of legumain is inhibited by an increase of cystatin E/M in the DJ-1-knockout mouse spleen, cerebrum and heart

Legumain (EC 3.4.22.34) is an asparaginyl endopeptidase. Legumain activity has been detected in various mouse tissues including the kidney, spleen and epididymis. Legumain is overexpressed in the majority of human solid tumors and transcription of the legumain gene is regulated by the p53 tumor supp...

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Detalles Bibliográficos
Autores principales: Yamane, Takuya, Kozuka, Miyuki, Yamamoto, Yoshio, Nakano, Yoshihisa, Nakagaki, Takenori, Ohkubo, Iwao, Ariga, Hiroyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614579/
https://www.ncbi.nlm.nih.gov/pubmed/28956004
http://dx.doi.org/10.1016/j.bbrep.2016.12.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614579/
https://www.ncbi.nlm.nih.gov/pubmed/28956004
http://dx.doi.org/10.1016/j.bbrep.2016.12.010

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