Development of a subunit vaccine for prevention of Clostridium difficile associated diseases: Biophysical characterization of toxoids A and B

Inactivation of bacterial toxins for use in human vaccines traditionally is achieved by treatment with formaldehyde. In contrast, the bivalent experimental vaccine for the prevention of C. difficile infections (CDI) that is currently being evaluated in clinical trials was produced using a different...

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Detalles Bibliográficos
Autores principales: Gribenko, Alexey, Severina, Elena, Sidhu, Maninder K., Jansen, Kathrin U., Green, Bruce A., Matsuka, Yury V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614615/
https://www.ncbi.nlm.nih.gov/pubmed/28956005
http://dx.doi.org/10.1016/j.bbrep.2016.12.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614615/
https://www.ncbi.nlm.nih.gov/pubmed/28956005
http://dx.doi.org/10.1016/j.bbrep.2016.12.015

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