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Scaffold-free 3D bio-printed human liver tissue stably maintains metabolic functions useful for drug discovery

The liver plays a central role in metabolism. Although many studies have described in vitro liver models for drug discovery, to date, no model has been described that can stably maintain liver function. Here, we used a unique, scaffold-free 3D bio-printing technology to construct a small portion of...

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Detalles Bibliográficos
Autores principales: Kizawa, Hideki, Nagao, Eri, Shimamura, Mitsuru, Zhang, Guangyuan, Torii, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614670/
https://www.ncbi.nlm.nih.gov/pubmed/28955746
http://dx.doi.org/10.1016/j.bbrep.2017.04.004