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TRIM25 in the Regulation of the Antiviral Innate Immunity

TRIM25 is an E3 ubiquitin ligase enzyme that is involved in various cellular processes, including regulation of the innate immune response against viruses. TRIM25-mediated ubiquitination of the cytosolic pattern recognition receptor RIG-I is an essential step for initiation of the intracellular anti...

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Detalles Bibliográficos
Autores principales: Martín-Vicente, María, Medrano, Luz M., Resino, Salvador, García-Sastre, Adolfo, Martínez, Isidoro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614919/
https://www.ncbi.nlm.nih.gov/pubmed/29018447
http://dx.doi.org/10.3389/fimmu.2017.01187