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Efficient engineering of chromosomal ribosome binding site libraries in mismatch repair proficient Escherichia coli
Multiplexed gene expression optimization via modulation of gene translation efficiency through ribosome binding site (RBS) engineering is a valuable approach for optimizing artificial properties in bacteria, ranging from genetic circuits to production pathways. Established algorithms design smart RB...
Autores principales: | Oesterle, Sabine, Gerngross, Daniel, Schmitt, Steven, Roberts, Tania Michelle, Panke, Sven |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615074/ https://www.ncbi.nlm.nih.gov/pubmed/28951570 http://dx.doi.org/10.1038/s41598-017-12395-3 |
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