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Single dose activated charcoal for gut decontamination: Application by medical non-professionals -a prospective study on availability and practicability

CONTEXT: Oral activated charcoal (AC) for toxin absorption should be applied as soon as possible. Extra-hospital AC-application on site by medical laypersons with pre-emptive obtained AC may save time, but may be inferior to AC-application by medical professionals. OBJECTIVE: 1) Availability and inc...

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Autores principales: Pfab, Rudolf, Schmoll, Sabrina, Dostal, Gabriele, Stenzel, Jochen, Hapfelmeier, Alexander, Eyer, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615092/
https://www.ncbi.nlm.nih.gov/pubmed/28959624
http://dx.doi.org/10.1016/j.toxrep.2016.12.007
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author Pfab, Rudolf
Schmoll, Sabrina
Dostal, Gabriele
Stenzel, Jochen
Hapfelmeier, Alexander
Eyer, Florian
author_facet Pfab, Rudolf
Schmoll, Sabrina
Dostal, Gabriele
Stenzel, Jochen
Hapfelmeier, Alexander
Eyer, Florian
author_sort Pfab, Rudolf
collection PubMed
description CONTEXT: Oral activated charcoal (AC) for toxin absorption should be applied as soon as possible. Extra-hospital AC-application on site by medical laypersons with pre-emptive obtained AC may save time, but may be inferior to AC-application by medical professionals. OBJECTIVE: 1) Availability and incidence of pre-emptive stockpiling of AC on site in the German region Bavaria 2) time saved by AC-stockpiling and application on site, 3) quality of AC-application defined by completeness of the applied AC-dose, time needed, incidence of side-effects in lay-care and in professional-care, considering confounding variables: AC-formulation/powder/tablets, recommended AC-dose, patient’s age. METHOD: telephone-interviews in cases with AC-recommendation by a Poison Information Centre (PIC). Lay-care was suggested according to risk-assessment by PIC. Ingestion sites were classified as either apt for AC-stockpiling or not apt. RESULTS: 1) availability: In Bavaria only 20%–22% of eligible cases had AC on-hand, 2) time-saving was at least 14 min. 3) Lay-care/professional-care or patient’s age had no significant influence on the completeness of the applied AC-dose, which was higher with AC as powder but negatively correlated with the recommended AC-dose. No significant difference was seen with time needed for application and incidence of side-effects. CONCLUSION: pre-emptive AC-stocking should be encouraged.
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spelling pubmed-56150922017-09-28 Single dose activated charcoal for gut decontamination: Application by medical non-professionals -a prospective study on availability and practicability Pfab, Rudolf Schmoll, Sabrina Dostal, Gabriele Stenzel, Jochen Hapfelmeier, Alexander Eyer, Florian Toxicol Rep Article CONTEXT: Oral activated charcoal (AC) for toxin absorption should be applied as soon as possible. Extra-hospital AC-application on site by medical laypersons with pre-emptive obtained AC may save time, but may be inferior to AC-application by medical professionals. OBJECTIVE: 1) Availability and incidence of pre-emptive stockpiling of AC on site in the German region Bavaria 2) time saved by AC-stockpiling and application on site, 3) quality of AC-application defined by completeness of the applied AC-dose, time needed, incidence of side-effects in lay-care and in professional-care, considering confounding variables: AC-formulation/powder/tablets, recommended AC-dose, patient’s age. METHOD: telephone-interviews in cases with AC-recommendation by a Poison Information Centre (PIC). Lay-care was suggested according to risk-assessment by PIC. Ingestion sites were classified as either apt for AC-stockpiling or not apt. RESULTS: 1) availability: In Bavaria only 20%–22% of eligible cases had AC on-hand, 2) time-saving was at least 14 min. 3) Lay-care/professional-care or patient’s age had no significant influence on the completeness of the applied AC-dose, which was higher with AC as powder but negatively correlated with the recommended AC-dose. No significant difference was seen with time needed for application and incidence of side-effects. CONCLUSION: pre-emptive AC-stocking should be encouraged. Elsevier 2016-12-31 /pmc/articles/PMC5615092/ /pubmed/28959624 http://dx.doi.org/10.1016/j.toxrep.2016.12.007 Text en © 2016 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Pfab, Rudolf
Schmoll, Sabrina
Dostal, Gabriele
Stenzel, Jochen
Hapfelmeier, Alexander
Eyer, Florian
Single dose activated charcoal for gut decontamination: Application by medical non-professionals -a prospective study on availability and practicability
title Single dose activated charcoal for gut decontamination: Application by medical non-professionals -a prospective study on availability and practicability
title_full Single dose activated charcoal for gut decontamination: Application by medical non-professionals -a prospective study on availability and practicability
title_fullStr Single dose activated charcoal for gut decontamination: Application by medical non-professionals -a prospective study on availability and practicability
title_full_unstemmed Single dose activated charcoal for gut decontamination: Application by medical non-professionals -a prospective study on availability and practicability
title_short Single dose activated charcoal for gut decontamination: Application by medical non-professionals -a prospective study on availability and practicability
title_sort single dose activated charcoal for gut decontamination: application by medical non-professionals -a prospective study on availability and practicability
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615092/
https://www.ncbi.nlm.nih.gov/pubmed/28959624
http://dx.doi.org/10.1016/j.toxrep.2016.12.007
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