Evaluation of a human in vitro hepatocyte-NPC co-culture model for the prediction of idiosyncratic drug-induced liver injury: A pilot study

Interactions between hepatocytes and immune cells as well as inflammatory episodes are frequently discussed to play a critical role in the alteration of the individual susceptibility to idiosyncratic drug-induced liver injury (iDILI). To evaluate this hypothesis and to face the urgent need for predi...

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Detalles Bibliográficos
Autores principales: Granitzny, Anne, Knebel, Jan, Müller, Meike, Braun, Armin, Steinberg, Pablo, Dasenbrock, Clemens, Hansen, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615103/
https://www.ncbi.nlm.nih.gov/pubmed/28959630
http://dx.doi.org/10.1016/j.toxrep.2017.02.001

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