Cargando…

p-Benzoquinone initiates non-invasive urothelial cancer through aberrant tyrosine phosphorylation of EGFR, MAP kinase activation and cell cycle deregulation: Prevention by vitamin C

According to WHO classification system, non-invasive urothelial carcinoma represents urothelial carcinoma in situ (CIS) and dysplasia. Dysplastic urothelium often progresses to CIS that further advances to urothelial carcinoma (UC). The strongest risk factor for UC is cigarette smoking. However, the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ganguly, Shinjini, Chandra, Ayan, Chattopadhyay, Dhruba J., Chatterjee, Indu B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615141/ https://www.ncbi.nlm.nih.gov/pubmed/28959653 http://dx.doi.org/10.1016/j.toxrep.2017.06.005

Ejemplares similares

Pathobiology of cigarette smoke-induced invasive cancer of the renal pelvis and its prevention by vitamin C
por: Ganguly, Shinjini, et al.
Publicado: (2018)

Molecular Mechanisms of Cigarette Smoke-Induced Proliferation of Lung Cells and Prevention by Vitamin C
por: Dey, Neekkan, et al.
Publicado: (2011)

Anti-p-benzoquinone antibody level as a prospective biomarker to identify smokers at risk for COPD
por: Banerjee, Santanu, et al.
Publicado: (2017)

Molecular and Cellular Mechanisms of Cigarette Smoke-Induced Myocardial Injury: Prevention by Vitamin C
por: Das, Archita, et al.
Publicado: (2012)

o-Benzoquinone dioxime
por: Gervasio, Giuliana, et al.
Publicado: (2010)

Interaction of p-benzoquinone with hemoglobin in smoker’s blood causes alteration of structure and loss of oxygen binding capacity
por: Ghosh, Arunava, et al.
Publicado: (2016)

Aberrant Elevation of Tyrosine‐specific Phosphorylation in Human Gastric Cancer Cells
por: Takeshima, Eisuke, et al.
Publicado: (1991)

EGFR Regulates the Hippo pathway by promoting the tyrosine phosphorylation of MOB1
por: Ando, Toshinori, et al.
Publicado: (2021)

Retraction: Causation of Cigarette Smoke–induced Emphysema by p-Benzoquinone and Its Prevention by Vitamin C
Publicado: (2021)

Alteration in tyrosine phosphorylation of cardiac proteome and EGFR pathway contribute to hypertrophic cardiomyopathy
por: Xu, Mingguo, et al.
Publicado: (2022)

Harvestman Phenols and Benzoquinones: Characterisation and Biosynthetic Pathway
por: Rocha, Daniele F. O., et al.
Publicado: (2013)

Effects of Benzoquinones on Radicles of Orobanche and Phelipanche Species
por: Fernández-Aparicio, Mónica, et al.
Publicado: (2021)

Deregulated FADD expression and phosphorylation in T-cell lymphoblastic lymphoma
por: Marín-Rubio, José L., et al.
Publicado: (2016)

Palladium-Catalyzed Direct C=H Functionalization of Benzoquinone**
por: Walker, Sarah E, et al.
Publicado: (2014)

A mechanism for 1,4-Benzoquinone-induced genotoxicity
por: Son, Mi Young, et al.
Publicado: (2016)

Benzoquinone Enhances Hyperpolarization of Surface Alcohols with Para-Hydrogen
por: Norcott, Philip L.
Publicado: (2023)

Histone deacetylase 8 is deregulated in urothelial cancer but not a target for efficient treatment
por: Lehmann, Maria, et al.
Publicado: (2014)

The vitamin D system is deregulated in pancreatic diseases
por: Hummel, Doris, et al.
Publicado: (2014)

Deregulated Gab2 phosphorylation mediates aberrant AKT and STAT3 signaling upon PIK3R1 loss in ovarian cancer
por: Li, Xinran, et al.
Publicado: (2019)

Novel Tyrosine Kinase Targets in Urothelial Carcinoma
por: Torres-Jiménez, Javier, et al.
Publicado: (2021)

Identification of benzoquinones in pretreated lignocellulosic feedstocks and inhibitory effects on yeast
por: Stagge, Stefan, et al.
Publicado: (2015)

Role of p-Benzoquinone in the Synthesis of a Conducting Polymer, Polyaniline
por: Bláha, Michal, et al.
Publicado: (2019)

Synthesis and optoelectronic properties of benzoquinone-based donor–acceptor compounds
por: Sutherland, Daniel R, et al.
Publicado: (2019)

Inhibition and crosslinking of the selenoprotein thioredoxin reductase-1 by p-benzoquinone
por: Shu, Nan, et al.
Publicado: (2019)

Addition of Vindoline to p-Benzoquinone: Regiochemistry, Stereochemistry and Symmetry Considerations
por: Ali, Shamsher, et al.
Publicado: (2021)

Aminoquinolones and Their Benzoquinone Dimer Hybrids as Modulators of Prion Protein Conversion
por: Costa, Amanda Rodrigues Pinto, et al.
Publicado: (2022)

TOPK promotes lung cancer resistance to EGFR tyrosine kinase inhibitors by phosphorylating and activating c-Jun
por: Li, Ying, et al.
Publicado: (2016)

Deregulation of Circular RNAs in Cancer From the Perspectives of Aberrant Biogenesis, Transport and Removal
por: Wu, Qiongqiong, et al.
Publicado: (2019)

Cellular and molecular mechanisms of cigarette smoke-induced lung damage and prevention by vitamin C
por: Banerjee, Shuvojit, et al.
Publicado: (2008)

Derivatives of a benzoquinone acyl hydrazone with activity against Toxoplasma gondii
por: Sanford, A.G., et al.
Publicado: (2018)

Novel Anti-Aging Benzoquinone Derivatives from Onosma bracteatum Wall
por: Farooq, Umer, et al.
Publicado: (2019)

Antifungal Activity of Benzoquinones Produced by Tribolium castaneum in Maize-Associated Fungi
por: Duarte, Sónia, et al.
Publicado: (2022)

Theoretical Investigation of Regiodivergent Addition of Anilines and Phenolates to p-Benzoquinone Ring
por: Da Silva, Haroldo C., et al.
Publicado: (2022)

EGFR-dependent tyrosine phosphorylation of integrin β4 is not required for downstream signaling events in cancer cell lines
por: te Molder, Lisa, et al.
Publicado: (2021)

Tyrosine phosphorylation and bacterial virulence
por: Whitmore, Sarah E, et al.
Publicado: (2012)

PCC0208027, a novel tyrosine kinase inhibitor, inhibits tumor growth of NSCLC by targeting EGFR and HER2 aberrations
por: Dong, Qiuju, et al.
Publicado: (2019)

Aberrantly Expressed OTX Homeobox Genes Deregulate B-Cell Differentiation in Hodgkin Lymphoma
por: Nagel, Stefan, et al.
Publicado: (2015)

Protein tyrosine phosphatase SHP-1 sensitizes EGFR/HER-2 positive breast cancer cells to trastuzumab through modulating phosphorylation of EGFR and HER-2
por: Wu, Yifen, et al.
Publicado: (2015)

Induction of Tyrosine Phosphorylation of UV-Activated EGFR by the Beta-Human Papillomavirus Type 8 E6 Leads to Papillomatosis
por: Taute, Stefanie, et al.
Publicado: (2017)

Aberrant Regulation of HDAC2 Mediates Proliferation of Hepatocellular Carcinoma Cells by Deregulating Expression of G1/S Cell Cycle Proteins
por: Noh, Ji Heon, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_c9bpndq2hlessklbbjdipbd6oi