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p-Benzoquinone initiates non-invasive urothelial cancer through aberrant tyrosine phosphorylation of EGFR, MAP kinase activation and cell cycle deregulation: Prevention by vitamin C

According to WHO classification system, non-invasive urothelial carcinoma represents urothelial carcinoma in situ (CIS) and dysplasia. Dysplastic urothelium often progresses to CIS that further advances to urothelial carcinoma (UC). The strongest risk factor for UC is cigarette smoking. However, the...

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Detalles Bibliográficos
Autores principales: Ganguly, Shinjini, Chandra, Ayan, Chattopadhyay, Dhruba J., Chatterjee, Indu B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615141/
https://www.ncbi.nlm.nih.gov/pubmed/28959653
http://dx.doi.org/10.1016/j.toxrep.2017.06.005

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