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Glioma cell fate decisions mediated by Dll1-Jag1-Fringe in Notch1 signaling pathway
BACKGROUND: The Notch family of proteins plays a vital role in determining cell fates, such as proliferation, differentiation, and apoptosis. It has been shown that Notch1 and its ligands, Dll1 and Jag1, are overexpressed in many glioma cell lines and primary human gliomas. The roles of Notch1 in so...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615248/ https://www.ncbi.nlm.nih.gov/pubmed/28950865 http://dx.doi.org/10.1186/s12918-017-0457-6 |