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Glioma cell fate decisions mediated by Dll1-Jag1-Fringe in Notch1 signaling pathway

BACKGROUND: The Notch family of proteins plays a vital role in determining cell fates, such as proliferation, differentiation, and apoptosis. It has been shown that Notch1 and its ligands, Dll1 and Jag1, are overexpressed in many glioma cell lines and primary human gliomas. The roles of Notch1 in so...

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Detalles Bibliográficos
Autores principales: Shi, Xiaofei, Wang, Ruiqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615248/
https://www.ncbi.nlm.nih.gov/pubmed/28950865
http://dx.doi.org/10.1186/s12918-017-0457-6

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